GISTs: From the History to the Tailored Therapy
نویسندگان
چکیده
منابع مشابه
بررسی مورفولوژی و ایمونوهیستوشیمیایی تومورهای استرومایی لوله گوارش و ارزش بروز c-kit در تشخیص هیستومورفولوژیک آنها
Background & Aim: Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumors of gastrointestinal tract. They are known to express c-kit, which is important in their diagnosis and treatment. The aim of our study was to assess the morphologic and immunohistochemical features of gastrointestinal stromal tumors and the significance of c-kit expression in them. Materials and M...
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HER family has been implicated in a number of malignant tumors for predicting prognosis and potential targeted therapy purposes, however, the prognostic roles of HER family in GISTs have not been elaborated yet. Our study aims to fully evaluate the prognostic value of HER family in GIST patients and efficacy of imatinib adjuvant therapy. For HER family expression detection, qPCR were used in 33...
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